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Американские ученые сообщили об успехе первых клинических испытаний препарата NK-лимфоцитов с химерным антигенным рецептором (CAR-NK-клеток) при В-клеточной лимфоме. Его изготавливают из донорских индуцированных плюрипотентных стволовых клеток (iPSC) и поставляют в готовом виде, а не получают путем модификации лимфоцитов пациента. Это позволяет стандартизовать и удешевить производство, а пациента избавить от лишнего ожидания лечения. Препарат не уступал по эффективности CAR-T-терапии, при этом гораздо реже вызывал синдром выброса цитокинов, а нейротоксичности не наблюдалось вообще
Американские ученые сообщили об успехе первых клинических испытаний препарата NK-лимфоцитов с химерным антигенным рецептором (CAR-NK-клеток) при В-клеточной лимфоме. Его изготавливают из донорских индуцированных плюрипотентных стволовых клеток (iPSC) и поставляют в готовом виде, а не получают путем модификации лимфоцитов пациента. Это позволяет стандартизовать и удешевить производство, а пациента избавить от лишнего ожидания лечения. Препарат не уступал по эффективности CAR-T-терапии, при этом гораздо реже вызывал синдром выброса цитокинов, а нейротоксичности не наблюдалось вообще
At its heart, Telegram is little more than a messaging app like WhatsApp or Signal. But it also offers open channels that enable a single user, or a group of users, to communicate with large numbers in a method similar to a Twitter account. This has proven to be both a blessing and a curse for Telegram and its users, since these channels can be used for both good and ill. Right now, as Wired reports, the app is a key way for Ukrainians to receive updates from the government during the invasion. The picture was mixed overseas. Hong Kong’s Hang Seng Index fell 1.6%, under pressure from U.S. regulatory scrutiny on New York-listed Chinese companies. Stocks were more buoyant in Europe, where Frankfurt’s DAX surged 1.4%. The next bit isn’t clear, but Durov reportedly claimed that his resignation, dated March 21st, was an April Fools’ prank. TechCrunch implies that it was a matter of principle, but it’s hard to be clear on the wheres, whos and whys. Similarly, on April 17th, the Moscow Times quoted Durov as saying that he quit the company after being pressured to reveal account details about Ukrainians protesting the then-president Viktor Yanukovych. The War on Fakes channel has repeatedly attempted to push conspiracies that footage from Ukraine is somehow being falsified. One post on the channel from February 24 claimed without evidence that a widely viewed photo of a Ukrainian woman injured in an airstrike in the city of Chuhuiv was doctored and that the woman was seen in a different photo days later without injuries. The post, which has over 600,000 views, also baselessly claimed that the woman's blood was actually makeup or grape juice. In 2014, Pavel Durov fled the country after allies of the Kremlin took control of the social networking site most know just as VK. Russia's intelligence agency had asked Durov to turn over the data of anti-Kremlin protesters. Durov refused to do so.
from es
