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🔴 Oneway for Don't eat me signal is an interaction between CD47 and SIRPalpha. SIRP family has three different subtypes include Alpha, Beta, and Gamma.
🟠 In cancer cells interaction between SIRPalpha and CD inhibits macrophages to select cancer cells and macrophage phagocytosis and also this mechanism help cancer cells to evade the immunity.
🟡 Many studies shown that overexpression and higher levels of CD47 in tumor cells surface than non-malignant cells.
🟢 By exploiting the "Don't eat me" signal, cancer cells utilize CD47's overexpression to evade immune cell surveillance and clearance, making CD47 a potential target for novel anti-tumor therapies.
🔴 Oneway for Don't eat me signal is an interaction between CD47 and SIRPalpha. SIRP family has three different subtypes include Alpha, Beta, and Gamma.
🟠 In cancer cells interaction between SIRPalpha and CD inhibits macrophages to select cancer cells and macrophage phagocytosis and also this mechanism help cancer cells to evade the immunity.
🟡 Many studies shown that overexpression and higher levels of CD47 in tumor cells surface than non-malignant cells.
🟢 By exploiting the "Don't eat me" signal, cancer cells utilize CD47's overexpression to evade immune cell surveillance and clearance, making CD47 a potential target for novel anti-tumor therapies.
The original Telegram channel has expanded into a web of accounts for different locations, including specific pages made for individual Russian cities. There's also an English-language website, which states it is owned by the people who run the Telegram channels. Now safely in France with his spouse and three of his children, Kliuchnikov scrolls through Telegram to learn about the devastation happening in his home country. The channel appears to be part of the broader information war that has developed following Russia's invasion of Ukraine. The Kremlin has paid Russian TikTok influencers to push propaganda, according to a Vice News investigation, while ProPublica found that fake Russian fact check videos had been viewed over a million times on Telegram. And while money initially moved into stocks in the morning, capital moved out of safe-haven assets. The price of the 10-year Treasury note fell Friday, sending its yield up to 2% from a March closing low of 1.73%. False news often spreads via public groups, or chats, with potentially fatal effects.
from fr
