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Don't Eat Me!⛔️

🔴 Oneway for Don't eat me signal is an interaction between CD47 and SIRPalpha.
SIRP family has three different subtypes include Alpha, Beta, and Gamma.

🟠 In cancer cells interaction between SIRPalpha and CD inhibits macrophages to select cancer cells and macrophage phagocytosis and also this mechanism help cancer cells to evade the immunity.

🟡 Many studies shown that overexpression and higher levels of CD47 in tumor cells surface than non-malignant cells.

🟢 By exploiting the "Don't eat me" signal, cancer cells utilize CD47's overexpression to evade immune cell surveillance and clearance, making CD47 a potential target for novel anti-tumor therapies.

📄 Reference: https://doi.org/10.1016%2Fj.heliyon.2023.e20507

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929 viewsSep 23, 2024 at 18:52

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Create: 2024-09-23
Last Update: 2025-01-23 22:41:03

Don't Eat Me!⛔️

🔴 Oneway for Don't eat me signal is an interaction between CD47 and SIRPalpha.
SIRP family has three different subtypes include Alpha, Beta, and Gamma.

🟠 In cancer cells interaction between SIRPalpha and CD inhibits macrophages to select cancer cells and macrophage phagocytosis and also this mechanism help cancer cells to evade the immunity.

🟡 Many studies shown that overexpression and higher levels of CD47 in tumor cells surface than non-malignant cells.

🟢 By exploiting the "Don't eat me" signal, cancer cells utilize CD47's overexpression to evade immune cell surveillance and clearance, making CD47 a potential target for novel anti-tumor therapies.

📄 Reference: https://doi.org/10.1016%2Fj.heliyon.2023.e20507

🆔 Follow us:
@Oncologylearn
@ResearchGroup1401

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Date: 2025-01-23|

Sebi said data, emails and other documents are being retrieved from the seized devices and detailed investigation is in progress. Elsewhere, version 8.6 of Telegram integrates the in-app camera option into the gallery, while a new navigation bar gives quick access to photos, files, location sharing, and more. "Markets were cheering this economic recovery and return to strong economic growth, but the cheers will turn to tears if the inflation outbreak pushes businesses and consumers to the brink of recession," he added. Some people used the platform to organize ahead of the storming of the U.S. Capitol in January 2021, and last month Senator Mark Warner sent a letter to Durov urging him to curb Russian information operations on Telegram. He adds: "Telegram has become my primary news source."
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