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暴力引发的基因表观遗传能持续数代

2025-02-28 18:21 by 彗星来临

1982 年,叙利亚政府军在老阿萨德的命令下在哈马市屠杀了数万本国居民。40 年后,反叛武装借助大屠杀的记忆推翻了阿萨德家族的统治。这次大屠杀的记忆也印刻了基因里,首次在人类身上提供了压力跨代遗传的证据。我们的基因本身不会因为生活经历而改变,但基因表达会。为了适应压力环境,细胞会在基因上添加化学标记以改变其行为。研究人员跟踪了叙利亚移民家族的三代人,部分家族经历了哈马市暴力袭击事件,部分家庭没有。研究人员从 48 个家庭 138 人身上收集了遗传样本,分析了 DNA 的表观遗传修饰。在哈马幸存者的孙辈中,研究人员发现基因组中有 14 个区域因祖母所经历的暴力事件而发生改变,表明压力引起的表观遗传变化确实能在多代人中间遗传。暂时不清楚表观遗传变化对人生活的影响。此前有研究指出饥荒引发的表观遗传变化会增加后代在成年后肥胖的几率。

Eurekalert:Violence alters human genes for generations, researchers discover

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暴力引发的基因表观遗传能持续数代

2025-02-28 18:21 by 彗星来临

1982 年,叙利亚政府军在老阿萨德的命令下在哈马市屠杀了数万本国居民。40 年后,反叛武装借助大屠杀的记忆推翻了阿萨德家族的统治。这次大屠杀的记忆也印刻了基因里,首次在人类身上提供了压力跨代遗传的证据。我们的基因本身不会因为生活经历而改变,但基因表达会。为了适应压力环境,细胞会在基因上添加化学标记以改变其行为。研究人员跟踪了叙利亚移民家族的三代人,部分家族经历了哈马市暴力袭击事件,部分家庭没有。研究人员从 48 个家庭 138 人身上收集了遗传样本,分析了 DNA 的表观遗传修饰。在哈马幸存者的孙辈中,研究人员发现基因组中有 14 个区域因祖母所经历的暴力事件而发生改变,表明压力引起的表观遗传变化确实能在多代人中间遗传。暂时不清楚表观遗传变化对人生活的影响。此前有研究指出饥荒引发的表观遗传变化会增加后代在成年后肥胖的几率。

Eurekalert:Violence alters human genes for generations, researchers discover

#生物技术

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Since January 2022, the SC has received a total of 47 complaints and enquiries on illegal investment schemes promoted through Telegram. These fraudulent schemes offer non-existent investment opportunities, promising very attractive and risk-free returns within a short span of time. They commonly offer unrealistic returns of as high as 1,000% within 24 hours or even within a few hours. Markets continued to grapple with the economic and corporate earnings implications relating to the Russia-Ukraine conflict. “We have a ton of uncertainty right now,” said Stephanie Link, chief investment strategist and portfolio manager at Hightower Advisors. “We’re dealing with a war, we’re dealing with inflation. We don’t know what it means to earnings.” The news also helped traders look past another report showing decades-high inflation and shake off some of the volatility from recent sessions. The Bureau of Labor Statistics' February Consumer Price Index (CPI) this week showed another surge in prices even before Russia escalated its attacks in Ukraine. The headline CPI — soaring 7.9% over last year — underscored the sticky inflationary pressures reverberating across the U.S. economy, with everything from groceries to rents and airline fares getting more expensive for everyday consumers. That hurt tech stocks. For the past few weeks, the 10-year yield has traded between 1.72% and 2%, as traders moved into the bond for safety when Russia headlines were ugly—and out of it when headlines improved. Now, the yield is touching its pandemic-era high. If the yield breaks above that level, that could signal that it’s on a sustainable path higher. Higher long-dated bond yields make future profits less valuable—and many tech companies are valued on the basis of profits forecast for many years in the future. But Telegram says people want to keep their chat history when they get a new phone, and they like having a data backup that will sync their chats across multiple devices. And that is why they let people choose whether they want their messages to be encrypted or not. When not turned on, though, chats are stored on Telegram's services, which are scattered throughout the world. But it has "disclosed 0 bytes of user data to third parties, including governments," Telegram states on its website.
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