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暴力引发的基因表观遗传能持续数代

2025-02-28 18:21 by 彗星来临

1982 年,叙利亚政府军在老阿萨德的命令下在哈马市屠杀了数万本国居民。40 年后,反叛武装借助大屠杀的记忆推翻了阿萨德家族的统治。这次大屠杀的记忆也印刻了基因里,首次在人类身上提供了压力跨代遗传的证据。我们的基因本身不会因为生活经历而改变,但基因表达会。为了适应压力环境,细胞会在基因上添加化学标记以改变其行为。研究人员跟踪了叙利亚移民家族的三代人,部分家族经历了哈马市暴力袭击事件,部分家庭没有。研究人员从 48 个家庭 138 人身上收集了遗传样本,分析了 DNA 的表观遗传修饰。在哈马幸存者的孙辈中,研究人员发现基因组中有 14 个区域因祖母所经历的暴力事件而发生改变,表明压力引起的表观遗传变化确实能在多代人中间遗传。暂时不清楚表观遗传变化对人生活的影响。此前有研究指出饥荒引发的表观遗传变化会增加后代在成年后肥胖的几率。

Eurekalert:Violence alters human genes for generations, researchers discover

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暴力引发的基因表观遗传能持续数代

2025-02-28 18:21 by 彗星来临

1982 年,叙利亚政府军在老阿萨德的命令下在哈马市屠杀了数万本国居民。40 年后,反叛武装借助大屠杀的记忆推翻了阿萨德家族的统治。这次大屠杀的记忆也印刻了基因里,首次在人类身上提供了压力跨代遗传的证据。我们的基因本身不会因为生活经历而改变,但基因表达会。为了适应压力环境,细胞会在基因上添加化学标记以改变其行为。研究人员跟踪了叙利亚移民家族的三代人,部分家族经历了哈马市暴力袭击事件,部分家庭没有。研究人员从 48 个家庭 138 人身上收集了遗传样本,分析了 DNA 的表观遗传修饰。在哈马幸存者的孙辈中,研究人员发现基因组中有 14 个区域因祖母所经历的暴力事件而发生改变,表明压力引起的表观遗传变化确实能在多代人中间遗传。暂时不清楚表观遗传变化对人生活的影响。此前有研究指出饥荒引发的表观遗传变化会增加后代在成年后肥胖的几率。

Eurekalert:Violence alters human genes for generations, researchers discover

#生物技术

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And indeed, volatility has been a hallmark of the market environment so far in 2022, with the S&P 500 still down more than 10% for the year-to-date after first sliding into a correction last month. The CBOE Volatility Index, or VIX, has held at a lofty level of more than 30. Some people used the platform to organize ahead of the storming of the U.S. Capitol in January 2021, and last month Senator Mark Warner sent a letter to Durov urging him to curb Russian information operations on Telegram. In addition, Telegram now supports the use of third-party streaming tools like OBS Studio and XSplit to broadcast live video, allowing users to add overlays and multi-screen layouts for a more professional look. The channel appears to be part of the broader information war that has developed following Russia's invasion of Ukraine. The Kremlin has paid Russian TikTok influencers to push propaganda, according to a Vice News investigation, while ProPublica found that fake Russian fact check videos had been viewed over a million times on Telegram. This ability to mix the public and the private, as well as the ability to use bots to engage with users has proved to be problematic. In early 2021, a database selling phone numbers pulled from Facebook was selling numbers for $20 per lookup. Similarly, security researchers found a network of deepfake bots on the platform that were generating images of people submitted by users to create non-consensual imagery, some of which involved children.
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