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🧠 Neurofibromatosis type 2

🖊 Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumour suppressor gene located on chromosome 22q.
🖊 It has a frequency of one in 25,000 livebirths and nearly 100% penetrance by 60 years of age.
🖊 Half of patients inherit a germline mutation from an affected parent and the remainder acquire a de novo mutation for neurofibromatosis type 2.
🖊 Patients develop nervous system tumours (schwannomas, meningiomas, ependymomas, astrocytomas, and neurofibromas), peripheral neuropathy, ophthalmological lesions (cataracts, epiretinal membranes, and retinal hamartomas), and cutaneous lesions (skin tumours).

🔎Source:
- Neurosurgery Board Review, Third Edition
- Neurofibromatosis type 2: A Review study

#MCQ #Neuroradiology
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☑️ Email: brainet.neuroscience@gmail.com
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474 viewsJan 24 at 17:05

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Create: 2025-01-24
Last Update: 2025-03-06 14:45:19

🧠 Neurofibromatosis type 2

🖊 Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumour suppressor gene located on chromosome 22q.
🖊 It has a frequency of one in 25,000 livebirths and nearly 100% penetrance by 60 years of age.
🖊 Half of patients inherit a germline mutation from an affected parent and the remainder acquire a de novo mutation for neurofibromatosis type 2.
🖊 Patients develop nervous system tumours (schwannomas, meningiomas, ependymomas, astrocytomas, and neurofibromas), peripheral neuropathy, ophthalmological lesions (cataracts, epiretinal membranes, and retinal hamartomas), and cutaneous lesions (skin tumours).

🔎Source:
- Neurosurgery Board Review, Third Edition
- Neurofibromatosis type 2: A Review study

#MCQ #Neuroradiology
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
☑️ Instagram: @theBRAINet
☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org

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Date: 2025-03-06|

Also in the latest update is the ability for users to create a unique @username from the Settings page, providing others with an easy way to contact them via Search or their t.me/username link without sharing their phone number. Two days after Russia invaded Ukraine, an account on the Telegram messaging platform posing as President Volodymyr Zelenskiy urged his armed forces to surrender. The regulator took order for the search and seizure operation from Judge Purushottam B Jadhav, Sebi Special Judge / Additional Sessions Judge. So, uh, whenever I hear about Telegram, it’s always in relation to something bad. What gives? "The result is on this photo: fiery 'greetings' to the invaders," the Security Service of Ukraine wrote alongside a photo showing several military vehicles among plumes of black smoke.
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