Мою старую лингвистическую задачку использовали в Первой традиционной израильской олимпиады по лингвистике: https://israel-ling.org/olimpiada (Кстати, название "Первая традиционная" само по себе продолжает традицию "Первой традиционной московской олимпиады по языковедению и математике").
Обнаружил легкое побочное решение, которое не пришло мне в голову много лет назад. Да и саму задачу, видимо, можно было сделать элегантнее.
Так бывает. "Рибосома как депо цинка" (repression by zinc was predicted for genes encoding a variety of paralogs of ribosomal proteins. The original copies of all these proteins contain zinc-ribbon motifs and thus likely bind zinc, whereas these motifs are destroyed in zinc-regulated paralogs. We suggest that the induction of these paralogs in conditions of zinc starvation leads to their incorporation in a fraction of ribosomes instead of the original ribosomal proteins; the latter are then degraded with subsequent release of some zinc for the utilization by other proteins. Thus we predict a mechanism for maintaining zinc availability for essential enzymes, https://www.pnas.org/doi/10.1073/pnas.1733691100) было красивой, но слишком сложной идеей; в большинстве случаев все сводится к замене более эффективных цинк-зависимых белков на, видимо, менее эффективные цинк-независимые в условиях цинкового голодания. Впрочем, в некоторых случаях потом люди видели, что цинк действительно высвобождается для других белков ("Liberation of Zinc-Containing L31 (RpmE) from Ribosomes by Its Paralogous Gene Product, YtiA, in Bacillus subtilis" https://journals.asm.org/doi/10.1128/jb.188.7.2715-2720.2006).
Мою старую лингвистическую задачку использовали в Первой традиционной израильской олимпиады по лингвистике: https://israel-ling.org/olimpiada (Кстати, название "Первая традиционная" само по себе продолжает традицию "Первой традиционной московской олимпиады по языковедению и математике").
Обнаружил легкое побочное решение, которое не пришло мне в голову много лет назад. Да и саму задачу, видимо, можно было сделать элегантнее.
Так бывает. "Рибосома как депо цинка" (repression by zinc was predicted for genes encoding a variety of paralogs of ribosomal proteins. The original copies of all these proteins contain zinc-ribbon motifs and thus likely bind zinc, whereas these motifs are destroyed in zinc-regulated paralogs. We suggest that the induction of these paralogs in conditions of zinc starvation leads to their incorporation in a fraction of ribosomes instead of the original ribosomal proteins; the latter are then degraded with subsequent release of some zinc for the utilization by other proteins. Thus we predict a mechanism for maintaining zinc availability for essential enzymes, https://www.pnas.org/doi/10.1073/pnas.1733691100) было красивой, но слишком сложной идеей; в большинстве случаев все сводится к замене более эффективных цинк-зависимых белков на, видимо, менее эффективные цинк-независимые в условиях цинкового голодания. Впрочем, в некоторых случаях потом люди видели, что цинк действительно высвобождается для других белков ("Liberation of Zinc-Containing L31 (RpmE) from Ribosomes by Its Paralogous Gene Product, YtiA, in Bacillus subtilis" https://journals.asm.org/doi/10.1128/jb.188.7.2715-2720.2006).
BY Михаил Гельфанд
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If you initiate a Secret Chat, however, then these communications are end-to-end encrypted and are tied to the device you are using. That means it’s less convenient to access them across multiple platforms, but you are at far less risk of snooping. Back in the day, Secret Chats received some praise from the EFF, but the fact that its standard system isn’t as secure earned it some criticism. If you’re looking for something that is considered more reliable by privacy advocates, then Signal is the EFF’s preferred platform, although that too is not without some caveats. Channels are not fully encrypted, end-to-end. All communications on a Telegram channel can be seen by anyone on the channel and are also visible to Telegram. Telegram may be asked by a government to hand over the communications from a channel. Telegram has a history of standing up to Russian government requests for data, but how comfortable you are relying on that history to predict future behavior is up to you. Because Telegram has this data, it may also be stolen by hackers or leaked by an internal employee. The channel appears to be part of the broader information war that has developed following Russia's invasion of Ukraine. The Kremlin has paid Russian TikTok influencers to push propaganda, according to a Vice News investigation, while ProPublica found that fake Russian fact check videos had been viewed over a million times on Telegram. The S&P 500 fell 1.3% to 4,204.36, and the Dow Jones Industrial Average was down 0.7% to 32,943.33. The Dow posted a fifth straight weekly loss — its longest losing streak since 2019. The Nasdaq Composite tumbled 2.2% to 12,843.81. Though all three indexes opened in the green, stocks took a turn after a new report showed U.S. consumer sentiment deteriorated more than expected in early March as consumers' inflation expectations soared to the highest since 1981. Crude oil prices edged higher after tumbling on Thursday, when U.S. West Texas intermediate slid back below $110 per barrel after topping as much as $130 a barrel in recent sessions. Still, gas prices at the pump rose to fresh highs.
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