🧠 Neurofibromatosis type 2
🖊 Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumour suppressor gene located on chromosome 22q.
🖊 It has a frequency of one in 25,000 livebirths and nearly 100% penetrance by 60 years of age.
🖊 Half of patients inherit a germline mutation from an affected parent and the remainder acquire a de novo mutation for neurofibromatosis type 2.
🖊 Patients develop nervous system tumours (schwannomas, meningiomas, ependymomas, astrocytomas, and neurofibromas), peripheral neuropathy, ophthalmological lesions (cataracts, epiretinal membranes, and retinal hamartomas), and cutaneous lesions (skin tumours).
🔎Source:
- Neurosurgery Board Review, Third Edition
- Neurofibromatosis type 2: A Review study
#MCQ #Neuroradiology
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🖊 Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumour suppressor gene located on chromosome 22q.
🖊 It has a frequency of one in 25,000 livebirths and nearly 100% penetrance by 60 years of age.
🖊 Half of patients inherit a germline mutation from an affected parent and the remainder acquire a de novo mutation for neurofibromatosis type 2.
🖊 Patients develop nervous system tumours (schwannomas, meningiomas, ependymomas, astrocytomas, and neurofibromas), peripheral neuropathy, ophthalmological lesions (cataracts, epiretinal membranes, and retinal hamartomas), and cutaneous lesions (skin tumours).
🔎Source:
- Neurosurgery Board Review, Third Edition
- Neurofibromatosis type 2: A Review study
#MCQ #Neuroradiology
—————————————
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#Neuroanatomy
Most of the fibers of the stria terminalis originate from the...
Most of the fibers of the stria terminalis originate from the...
Anonymous Quiz
45%
Amygdala
7%
Anterior hypothalamus
21%
Arcuate nucleus
17%
Habenula
10%
Septal nuclei
🧠 Amygdala
🖊 The amygdala is a hub of subcortical region that is crucial in a wide array of affective and motivation-related behaviors.
🖊 While early research contributed significantly to our understanding of this region's extensive connections to other subcortical and cortical regions, recent methodological advances have enabled researchers to better understand the details of these circuits and their behavioral contributions.
🖊 Much of this work has focused specifically on investigating the role of amygdala circuits in social cognition. In this chapter, we review both long-standing knowledge and novel research on the amygdala's structure, function, and involvement in social cognition.
🔎Source:
- Neurosurgery Board Review, Third Edition
- Amygdala connectivity and implications for social cognition and disorders
#MCQ #Neuroanatomy
—————————————
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🖊 The amygdala is a hub of subcortical region that is crucial in a wide array of affective and motivation-related behaviors.
🖊 While early research contributed significantly to our understanding of this region's extensive connections to other subcortical and cortical regions, recent methodological advances have enabled researchers to better understand the details of these circuits and their behavioral contributions.
🖊 Much of this work has focused specifically on investigating the role of amygdala circuits in social cognition. In this chapter, we review both long-standing knowledge and novel research on the amygdala's structure, function, and involvement in social cognition.
🔎Source:
- Neurosurgery Board Review, Third Edition
- Amygdala connectivity and implications for social cognition and disorders
#MCQ #Neuroanatomy
—————————————
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Due to failure of what embryological stage of development is the abnormality on imaging demonstrated here most likely?
Anonymous Quiz
3%
Primary neurulation
3%
Disjunction
23%
Secondary neurulation
60%
Neuronal migration
10%
Gastrulation
🧠 Neuronal migration
🖊 Neuronal migration is a crucial process in brain development where neurons move from their origin to their final positions, essential for forming neural circuits and brain structure.
🖊 It involves stages such as neurogenesis, radial and tangential migration, and final positioning. Mechanisms include cell adhesion molecules, chemotaxis, and cytoskeletal dynamics.
🖊 Disorders related to this process include lissencephaly and autism spectrum disorders. Understanding neuronal migration is vital for insights into brain organization and neurological disorders.
🔎Source:
- Neurosurgery Board Review, Third Edition
- Neurogenesis, neuronal migration, and axon guidance
#MCQ #Neuroimaging
—————————————
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🖊 Neuronal migration is a crucial process in brain development where neurons move from their origin to their final positions, essential for forming neural circuits and brain structure.
🖊 It involves stages such as neurogenesis, radial and tangential migration, and final positioning. Mechanisms include cell adhesion molecules, chemotaxis, and cytoskeletal dynamics.
🖊 Disorders related to this process include lissencephaly and autism spectrum disorders. Understanding neuronal migration is vital for insights into brain organization and neurological disorders.
🔎Source:
- Neurosurgery Board Review, Third Edition
- Neurogenesis, neuronal migration, and axon guidance
#MCQ #Neuroimaging
—————————————
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☑️ Website: theBRAINet.org
🧠 Brainet is Recruiting New Members! 🌍🔬
Are you passionate about neuroscience and eager to contribute to a dynamic research community? BRAINet Research & Executive Group is now accepting new members! 🚀
We are looking for students, researchers, and enthusiasts with diverse skills, from neuroscience and data analysis to content creation and social media management. Whether you want to contribute scientifically or support our outreach activities, there’s a role for you!
📌 What You Can Contribute:
✅ Neuroscience research & data analysis
✅ Scientific writing & literature review
✅ Website & social media management
✅ Organizing events & community engagement
🔗 Apply now: [Google Form Link]
📅 Deadline: [March 1st, 2025]
Join us in exploring the fascinating world of brain science! 🧠✨ For any questions, feel free to reach out.
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
☑️ Instagram: @theBRAINet
☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
Are you passionate about neuroscience and eager to contribute to a dynamic research community? BRAINet Research & Executive Group is now accepting new members! 🚀
We are looking for students, researchers, and enthusiasts with diverse skills, from neuroscience and data analysis to content creation and social media management. Whether you want to contribute scientifically or support our outreach activities, there’s a role for you!
📌 What You Can Contribute:
✅ Neuroscience research & data analysis
✅ Scientific writing & literature review
✅ Website & social media management
✅ Organizing events & community engagement
🔗 Apply now: [Google Form Link]
📅 Deadline: [March 1st, 2025]
Join us in exploring the fascinating world of brain science! 🧠✨ For any questions, feel free to reach out.
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
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☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
🎉 New Publication Alert from BRAINet! 🎉
We're excited to announce our latest Brainet-affiliated research, “Telovelar vs. Transvermian Approach for the Fourth Ventricle Tumors: A Systematic Review and Meta-Analysis.” Published in Clinical Neurology and Neurosurgery (Vol. 240, 2024) and available online since March 26, 2024, this study provides an in-depth comparison of two key surgical approaches for fourth ventricle tumors, shedding light on their postoperative outcomes and complications.
Join us as we continue our series of research highlights and explore innovative insights in neurosurgery!
🔗 Read the full article
#Neurosurgery #Brainet #ClinicalResearch #Article #Publication
—————————————
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☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
We're excited to announce our latest Brainet-affiliated research, “Telovelar vs. Transvermian Approach for the Fourth Ventricle Tumors: A Systematic Review and Meta-Analysis.” Published in Clinical Neurology and Neurosurgery (Vol. 240, 2024) and available online since March 26, 2024, this study provides an in-depth comparison of two key surgical approaches for fourth ventricle tumors, shedding light on their postoperative outcomes and complications.
Join us as we continue our series of research highlights and explore innovative insights in neurosurgery!
🔗 Read the full article
#Neurosurgery #Brainet #ClinicalResearch #Article #Publication
—————————————
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🎉 Exciting Announcement from Brainet! 🎉
We are thrilled to share our very first publication with Brainet affiliation! This week, we feature the article titled:
"Management of Intercostal Artery Pseudoaneurysm Following Posterior Pedicle Screw Insertion: Illustrative Case"
Published in the Journal of Neurosurgery Case Lessons (Vol. 9, Issue 4, January 27, 2025), this paper highlights a rare vascular complication during spinal surgery and demonstrates innovative management techniques using Onyx embolization.
Stay tuned for more groundbreaking work from Brainet!
🔗 Read the full article
#Neuroscience #Brainet #ResearchInnovation #Article #Publication
—————————————
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☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
We are thrilled to share our very first publication with Brainet affiliation! This week, we feature the article titled:
"Management of Intercostal Artery Pseudoaneurysm Following Posterior Pedicle Screw Insertion: Illustrative Case"
Published in the Journal of Neurosurgery Case Lessons (Vol. 9, Issue 4, January 27, 2025), this paper highlights a rare vascular complication during spinal surgery and demonstrates innovative management techniques using Onyx embolization.
Stay tuned for more groundbreaking work from Brainet!
🔗 Read the full article
#Neuroscience #Brainet #ResearchInnovation #Article #Publication
—————————————
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#Neurosurgery
You are seeing a 55-year-old patient back in fol low-up 3 months after a gross total resection of a glioblastoma of the right frontal lobe. She has un dergone 60 Gy XRT and TMZ chemotherapy. Her tumor demonstrated MGMT promoter methyl ation. On her MRI there is evidence of a contrast enhancing nodule in the resection cavity.
You are seeing a 55-year-old patient back in fol low-up 3 months after a gross total resection of a glioblastoma of the right frontal lobe. She has un dergone 60 Gy XRT and TMZ chemotherapy. Her tumor demonstrated MGMT promoter methyl ation. On her MRI there is evidence of a contrast enhancing nodule in the resection cavity.
What is the likely cause of this finding?
Anonymous Quiz
17%
Postoperative blood products
22%
Tumor recurrence
57%
Pseudoprogression
4%
Ischemic stroke
🧠 Pseudoprogression
In MGMT promoter methylated GBM patients, contrast enhancement can be seen at roughly 3 months post gross total resection and Stupp reg imen. It is consistent with pseudoprogression and often decreases on subsequent imaging and symp toms can resolve with steroids. It is associated with radiation kill of the tumor. At this time there are no definitive imaging studies that can prove pseu doprogression vs tumor recurrence, but this is an active area of research.
🔎Source:
- Further Reading: Greenberg. Handbook of Neuro surgery. 8th edition, 2016, page 623.
#MCQ #Neurosurgery
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In MGMT promoter methylated GBM patients, contrast enhancement can be seen at roughly 3 months post gross total resection and Stupp reg imen. It is consistent with pseudoprogression and often decreases on subsequent imaging and symp toms can resolve with steroids. It is associated with radiation kill of the tumor. At this time there are no definitive imaging studies that can prove pseu doprogression vs tumor recurrence, but this is an active area of research.
🔎Source:
- Further Reading: Greenberg. Handbook of Neuro surgery. 8th edition, 2016, page 623.
#MCQ #Neurosurgery
—————————————
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BRAINet
🧠 Brainet is Recruiting New Members! 🌍🔬 Are you passionate about neuroscience and eager to contribute to a dynamic research community? BRAINet Research & Executive Group is now accepting new members! 🚀 We are looking for students, researchers, and enthusiasts…
🚨 Deadline Extended! 🚨
Good news! We've extended the application deadline for BRAINet Research & Executive Group Membership by 3 more days! ⏳✨
📅 New Deadline: March 4th, 2025
Don't miss this opportunity to join our growing neuroscience community! Apply now and be part of something impactful.
🔗 Apply here: Google Form Link
For any questions, feel free to reach out! 🧠💡
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
☑️ Instagram: @theBRAINet
☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
Good news! We've extended the application deadline for BRAINet Research & Executive Group Membership by 3 more days! ⏳✨
📅 New Deadline: March 4th, 2025
Don't miss this opportunity to join our growing neuroscience community! Apply now and be part of something impactful.
🔗 Apply here: Google Form Link
For any questions, feel free to reach out! 🧠💡
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
☑️ Instagram: @theBRAINet
☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
BRAINet
🧠 Brainet is Recruiting New Members! 🌍🔬 Are you passionate about neuroscience and eager to contribute to a dynamic research community? BRAINet Research & Executive Group is now accepting new members! 🚀 We are looking for students, researchers, and enthusiasts…
🚀 BRAINet Membership Application – Next Steps 🚀
The application deadline has passed, and we are truly grateful for the overwhelming interest and enthusiasm from all applicants! 🧠✨
We are now in the process of reviewing the submissions, and in the coming days, we will be reaching out to selected applicants to schedule interviews. Stay tuned for further updates!
Thank you for your dedication to neuroscience research and innovation!
we’re excited to build the future of BRAINet together! 💡🔬
#BRAINet #Neuroscience #Research #Collaboration
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
☑️ Instagram: @theBRAINet
☑️ Email: brainet.neuroscience@gmail.com
☑️ Website: theBRAINet.org
The application deadline has passed, and we are truly grateful for the overwhelming interest and enthusiasm from all applicants! 🧠✨
We are now in the process of reviewing the submissions, and in the coming days, we will be reaching out to selected applicants to schedule interviews. Stay tuned for further updates!
Thank you for your dedication to neuroscience research and innovation!
we’re excited to build the future of BRAINet together! 💡🔬
#BRAINet #Neuroscience #Research #Collaboration
—————————————
📍 Join us in BRAINet
☑️ Telegram: @theBRAINet
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