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SARS-CoV-2 Variant – United Kingdom of Great Britain and Northern Ireland
Disease Outbreak News
21 December 2020
SARS-CoV-2 VUI 202012/01 (Variant Under Investigation, year 2020, month 12, variant 01)
1108 cases infected (December 13)
Most COVID-19 cases from whom this variant has been identified have occurred in people under 60 years of age.
14 mutations resulting in amino acid changes and three deletions
Some of these mutations may influence the transmissibility of the virus in humans:
N501Y
P681H
the deletion at position 69/70
an estimated increase of between 40% and 70% in transmissibility (adding 0.4 to the basic reproduction number R0, bringing it to a range of 1.5 to 1.7)
The new VUI-202012/01 variant has been identified in several countries including Australia, Denmark, Italy, Iceland and the Netherlands
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