Синдром Дауна развивается, когда в кариотипе клеток присутствует лишняя 21 хромосома, полученная от матери. Японские ученые воспользовались технологией редактирования генома CRISPR-Cas9 и прицельно удалили лишнюю хромосому в клеточных культурах фибробластов и индуцированных плюрипотентных стволовых клеток с трисомией 21 с выходом почти в 40 процентов. О клиническом применении речи пока не идет, но получено подтверждение того, что потенциально это возможно
Синдром Дауна развивается, когда в кариотипе клеток присутствует лишняя 21 хромосома, полученная от матери. Японские ученые воспользовались технологией редактирования генома CRISPR-Cas9 и прицельно удалили лишнюю хромосому в клеточных культурах фибробластов и индуцированных плюрипотентных стволовых клеток с трисомией 21 с выходом почти в 40 процентов. О клиническом применении речи пока не идет, но получено подтверждение того, что потенциально это возможно
Andrey, a Russian entrepreneur living in Brazil who, fearing retaliation, asked that NPR not use his last name, said Telegram has become one of the few places Russians can access independent news about the war. The next bit isn’t clear, but Durov reportedly claimed that his resignation, dated March 21st, was an April Fools’ prank. TechCrunch implies that it was a matter of principle, but it’s hard to be clear on the wheres, whos and whys. Similarly, on April 17th, the Moscow Times quoted Durov as saying that he quit the company after being pressured to reveal account details about Ukrainians protesting the then-president Viktor Yanukovych. During the operations, Sebi officials seized various records and documents, including 34 mobile phones, six laptops, four desktops, four tablets, two hard drive disks and one pen drive from the custody of these persons. Telegram has become more interventionist over time, and has steadily increased its efforts to shut down these accounts. But this has also meant that the company has also engaged with lawmakers more generally, although it maintains that it doesn’t do so willingly. For instance, in September 2021, Telegram reportedly blocked a chat bot in support of (Putin critic) Alexei Navalny during Russia’s most recent parliamentary elections. Pavel Durov was quoted at the time saying that the company was obliged to follow a “legitimate” law of the land. He added that as Apple and Google both follow the law, to violate it would give both platforms a reason to boot the messenger from its stores. In the past, it was noticed that through bulk SMSes, investors were induced to invest in or purchase the stocks of certain listed companies.
from tw
