جایزه نوبل پزشکی یا فیزیولوژی امسال (2024) به صورت مشترک به Victor Ambros و Gary Ruvkun به خاطر کشف microRNA و نقش آن در تنظیم ژن بعد از رونویسی (post-transcriptional gene regulation) تعلق گرفت. (هر دو از آمریکا) (لینک)
مقالات کلیدی در این زمینه از این محققین:
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993;75(5):843-854. با 18413 استناد
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell. 1993;75(5):855-862. با 5650 استناد
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000;408(6808):86-89. با 3524 استناد
از سال ۱۹۰۱ تاکنون، ۱۱۴ بار جایزه نوبل پزشکی و فیزیولوژی به ۲۲۷ نفر (13 خانم) اهدا شده است. جوان ترین فرد، Frederick Banting با ۳۱ سال سن و مسن ترین فرد، Peyton Rous با ۸۷ سال سن بوده است.
جایزه نوبل پزشکی یا فیزیولوژی امسال (2024) به صورت مشترک به Victor Ambros و Gary Ruvkun به خاطر کشف microRNA و نقش آن در تنظیم ژن بعد از رونویسی (post-transcriptional gene regulation) تعلق گرفت. (هر دو از آمریکا) (لینک)
مقالات کلیدی در این زمینه از این محققین:
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993;75(5):843-854. با 18413 استناد
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell. 1993;75(5):855-862. با 5650 استناد
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000;408(6808):86-89. با 3524 استناد
از سال ۱۹۰۱ تاکنون، ۱۱۴ بار جایزه نوبل پزشکی و فیزیولوژی به ۲۲۷ نفر (13 خانم) اهدا شده است. جوان ترین فرد، Frederick Banting با ۳۱ سال سن و مسن ترین فرد، Peyton Rous با ۸۷ سال سن بوده است.
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