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暴力引发的基因表观遗传能持续数代

2025-02-28 18:21 by 彗星来临

1982 年,叙利亚政府军在老阿萨德的命令下在哈马市屠杀了数万本国居民。40 年后,反叛武装借助大屠杀的记忆推翻了阿萨德家族的统治。这次大屠杀的记忆也印刻了基因里,首次在人类身上提供了压力跨代遗传的证据。我们的基因本身不会因为生活经历而改变,但基因表达会。为了适应压力环境,细胞会在基因上添加化学标记以改变其行为。研究人员跟踪了叙利亚移民家族的三代人,部分家族经历了哈马市暴力袭击事件,部分家庭没有。研究人员从 48 个家庭 138 人身上收集了遗传样本,分析了 DNA 的表观遗传修饰。在哈马幸存者的孙辈中,研究人员发现基因组中有 14 个区域因祖母所经历的暴力事件而发生改变,表明压力引起的表观遗传变化确实能在多代人中间遗传。暂时不清楚表观遗传变化对人生活的影响。此前有研究指出饥荒引发的表观遗传变化会增加后代在成年后肥胖的几率。

Eurekalert:Violence alters human genes for generations, researchers discover

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暴力引发的基因表观遗传能持续数代

2025-02-28 18:21 by 彗星来临

1982 年,叙利亚政府军在老阿萨德的命令下在哈马市屠杀了数万本国居民。40 年后,反叛武装借助大屠杀的记忆推翻了阿萨德家族的统治。这次大屠杀的记忆也印刻了基因里,首次在人类身上提供了压力跨代遗传的证据。我们的基因本身不会因为生活经历而改变,但基因表达会。为了适应压力环境,细胞会在基因上添加化学标记以改变其行为。研究人员跟踪了叙利亚移民家族的三代人,部分家族经历了哈马市暴力袭击事件,部分家庭没有。研究人员从 48 个家庭 138 人身上收集了遗传样本,分析了 DNA 的表观遗传修饰。在哈马幸存者的孙辈中,研究人员发现基因组中有 14 个区域因祖母所经历的暴力事件而发生改变,表明压力引起的表观遗传变化确实能在多代人中间遗传。暂时不清楚表观遗传变化对人生活的影响。此前有研究指出饥荒引发的表观遗传变化会增加后代在成年后肥胖的几率。

Eurekalert:Violence alters human genes for generations, researchers discover

#生物技术

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What distinguishes the app from competitors is its use of what's known as channels: Public or private feeds of photos and videos that can be set up by one person or an organization. The channels have become popular with on-the-ground journalists, aid workers and Ukrainian President Volodymyr Zelenskyy, who broadcasts on a Telegram channel. The channels can be followed by an unlimited number of people. Unlike Facebook, Twitter and other popular social networks, there is no advertising on Telegram and the flow of information is not driven by an algorithm. As a result, the pandemic saw many newcomers to Telegram, including prominent anti-vaccine activists who used the app's hands-off approach to share false information on shots, a study from the Institute for Strategic Dialogue shows. Apparently upbeat developments in Russia's discussions with Ukraine helped at least temporarily send investors back into risk assets. Russian President Vladimir Putin said during a meeting with his Belarusian counterpart Alexander Lukashenko that there were "certain positive developments" occurring in the talks with Ukraine, according to a transcript of their meeting. Putin added that discussions were happening "almost on a daily basis." The account, "War on Fakes," was created on February 24, the same day Russian President Vladimir Putin announced a "special military operation" and troops began invading Ukraine. The page is rife with disinformation, according to The Atlantic Council's Digital Forensic Research Lab, which studies digital extremism and published a report examining the channel. You may recall that, back when Facebook started changing WhatsApp’s terms of service, a number of news outlets reported on, and even recommended, switching to Telegram. Pavel Durov even said that users should delete WhatsApp “unless you are cool with all of your photos and messages becoming public one day.” But Telegram can’t be described as a more-secure version of WhatsApp.
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