📝این مقاله SPLICE-q را به عنوان یک نرمافزار مبتنی بر Python برای تحلیل کارایی برش ژنهایی بهصورت گسترده با استفاده از دادههای توالییابی RNA (RNA-seq) معرفی میکند. Splicing، یک مرحلهی حیاتی در بیان ژن است که شامل حذف اینترونها از پیش RNA (pre-mRNA) برای تولید RNA بالغ میشود. این مطالعه به اهمیت اندازهگیری کارایی برش برای درک دینامیک آن و پیامدهای آن، بهویژه در زمینه بیماریهایی مانند سرطان، میپردازد.
📝این مقاله SPLICE-q را به عنوان یک نرمافزار مبتنی بر Python برای تحلیل کارایی برش ژنهایی بهصورت گسترده با استفاده از دادههای توالییابی RNA (RNA-seq) معرفی میکند. Splicing، یک مرحلهی حیاتی در بیان ژن است که شامل حذف اینترونها از پیش RNA (pre-mRNA) برای تولید RNA بالغ میشود. این مطالعه به اهمیت اندازهگیری کارایی برش برای درک دینامیک آن و پیامدهای آن، بهویژه در زمینه بیماریهایی مانند سرطان، میپردازد.
On Feb. 27, however, he admitted from his Russian-language account that "Telegram channels are increasingly becoming a source of unverified information related to Ukrainian events." These entities are reportedly operating nine Telegram channels with more than five million subscribers to whom they were making recommendations on selected listed scrips. Such recommendations induced the investors to deal in the said scrips, thereby creating artificial volume and price rise. Right now the digital security needs of Russians and Ukrainians are very different, and they lead to very different caveats about how to mitigate the risks associated with using Telegram. For Ukrainians in Ukraine, whose physical safety is at risk because they are in a war zone, digital security is probably not their highest priority. They may value access to news and communication with their loved ones over making sure that all of their communications are encrypted in such a manner that they are indecipherable to Telegram, its employees, or governments with court orders. The next bit isn’t clear, but Durov reportedly claimed that his resignation, dated March 21st, was an April Fools’ prank. TechCrunch implies that it was a matter of principle, but it’s hard to be clear on the wheres, whos and whys. Similarly, on April 17th, the Moscow Times quoted Durov as saying that he quit the company after being pressured to reveal account details about Ukrainians protesting the then-president Viktor Yanukovych. "Russians are really disconnected from the reality of what happening to their country," Andrey said. "So Telegram has become essential for understanding what's going on to the Russian-speaking world."
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