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Scientists at Yale University have developed BrainLM, the first foundation model for analyzing functional MRI brain recordings.

Here's what makes it revolutionary:

- Trained on 6,700 hours of brain activity recordings
- Uses self-supervised masked-prediction training
- Processes data from 77,298 fMRI samples
- Analyzes 424 brain regions simultaneously

Capabilities:

- Accurately predicts clinical variables like age, anxiety, and PTSD
- Forecasts future brain states
- Identifies functional networks without supervision
- Generates interpretable representations of brain activity patterns

What Sets It Apart:

- Generalizes well to new patients and external datasets
- Outperforms baseline models in clinical predictions
- Serves as a powerful "lens" for analyzing massive fMRI repositories
- Creates meaningful insights about brain organization

Potential Applications:
- Non-invasive assessment of cognitive health
- Early detection of psychiatric disorders
- Research tool for understanding brain dynamics
- Biomarker discovery for mental health conditions

Technical Implementation:

- Based on Transformer architecture
- Trained on UK Biobank and Human Connectome Project data
- Uses advanced preprocessing and brain parcellation techniques
- Employs state-of-the-art deep learning methods



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Scientists at Yale University have developed BrainLM, the first foundation model for analyzing functional MRI brain recordings.

Here's what makes it revolutionary:

- Trained on 6,700 hours of brain activity recordings
- Uses self-supervised masked-prediction training
- Processes data from 77,298 fMRI samples
- Analyzes 424 brain regions simultaneously

Capabilities:

- Accurately predicts clinical variables like age, anxiety, and PTSD
- Forecasts future brain states
- Identifies functional networks without supervision
- Generates interpretable representations of brain activity patterns

What Sets It Apart:

- Generalizes well to new patients and external datasets
- Outperforms baseline models in clinical predictions
- Serves as a powerful "lens" for analyzing massive fMRI repositories
- Creates meaningful insights about brain organization

Potential Applications:
- Non-invasive assessment of cognitive health
- Early detection of psychiatric disorders
- Research tool for understanding brain dynamics
- Biomarker discovery for mental health conditions

Technical Implementation:

- Based on Transformer architecture
- Trained on UK Biobank and Human Connectome Project data
- Uses advanced preprocessing and brain parcellation techniques
- Employs state-of-the-art deep learning methods

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Pavel Durov, Telegram's CEO, is known as "the Russian Mark Zuckerberg," for co-founding VKontakte, which is Russian for "in touch," a Facebook imitator that became the country's most popular social networking site. Russian President Vladimir Putin launched Russia's invasion of Ukraine in the early-morning hours of February 24, targeting several key cities with military strikes. Telegram does offer end-to-end encrypted communications through Secret Chats, but this is not the default setting. Standard conversations use the MTProto method, enabling server-client encryption but with them stored on the server for ease-of-access. This makes using Telegram across multiple devices simple, but also means that the regular Telegram chats you’re having with folks are not as secure as you may believe. Channels are not fully encrypted, end-to-end. All communications on a Telegram channel can be seen by anyone on the channel and are also visible to Telegram. Telegram may be asked by a government to hand over the communications from a channel. Telegram has a history of standing up to Russian government requests for data, but how comfortable you are relying on that history to predict future behavior is up to you. Because Telegram has this data, it may also be stolen by hackers or leaked by an internal employee. At this point, however, Durov had already been working on Telegram with his brother, and further planned a mobile-first social network with an explicit focus on anti-censorship. Later in April, he told TechCrunch that he had left Russia and had “no plans to go back,” saying that the nation was currently “incompatible with internet business at the moment.” He added later that he was looking for a country that matched his libertarian ideals to base his next startup.
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