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Scientists at Yale University have developed BrainLM, the first foundation model for analyzing functional MRI brain recordings.

Here's what makes it revolutionary:

- Trained on 6,700 hours of brain activity recordings
- Uses self-supervised masked-prediction training
- Processes data from 77,298 fMRI samples
- Analyzes 424 brain regions simultaneously

Capabilities:

- Accurately predicts clinical variables like age, anxiety, and PTSD
- Forecasts future brain states
- Identifies functional networks without supervision
- Generates interpretable representations of brain activity patterns

What Sets It Apart:

- Generalizes well to new patients and external datasets
- Outperforms baseline models in clinical predictions
- Serves as a powerful "lens" for analyzing massive fMRI repositories
- Creates meaningful insights about brain organization

Potential Applications:
- Non-invasive assessment of cognitive health
- Early detection of psychiatric disorders
- Research tool for understanding brain dynamics
- Biomarker discovery for mental health conditions

Technical Implementation:

- Based on Transformer architecture
- Trained on UK Biobank and Human Connectome Project data
- Uses advanced preprocessing and brain parcellation techniques
- Employs state-of-the-art deep learning methods



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Scientists at Yale University have developed BrainLM, the first foundation model for analyzing functional MRI brain recordings.

Here's what makes it revolutionary:

- Trained on 6,700 hours of brain activity recordings
- Uses self-supervised masked-prediction training
- Processes data from 77,298 fMRI samples
- Analyzes 424 brain regions simultaneously

Capabilities:

- Accurately predicts clinical variables like age, anxiety, and PTSD
- Forecasts future brain states
- Identifies functional networks without supervision
- Generates interpretable representations of brain activity patterns

What Sets It Apart:

- Generalizes well to new patients and external datasets
- Outperforms baseline models in clinical predictions
- Serves as a powerful "lens" for analyzing massive fMRI repositories
- Creates meaningful insights about brain organization

Potential Applications:
- Non-invasive assessment of cognitive health
- Early detection of psychiatric disorders
- Research tool for understanding brain dynamics
- Biomarker discovery for mental health conditions

Technical Implementation:

- Based on Transformer architecture
- Trained on UK Biobank and Human Connectome Project data
- Uses advanced preprocessing and brain parcellation techniques
- Employs state-of-the-art deep learning methods

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Telegram users are able to send files of any type up to 2GB each and access them from any device, with no limit on cloud storage, which has made downloading files more popular on the platform. Pavel Durov, a billionaire who embraces an all-black wardrobe and is often compared to the character Neo from "the Matrix," funds Telegram through his personal wealth and debt financing. And despite being one of the world's most popular tech companies, Telegram reportedly has only about 30 employees who defer to Durov for most major decisions about the platform. "And that set off kind of a battle royale for control of the platform that Durov eventually lost," said Nathalie Maréchal of the Washington advocacy group Ranking Digital Rights. If you initiate a Secret Chat, however, then these communications are end-to-end encrypted and are tied to the device you are using. That means it’s less convenient to access them across multiple platforms, but you are at far less risk of snooping. Back in the day, Secret Chats received some praise from the EFF, but the fact that its standard system isn’t as secure earned it some criticism. If you’re looking for something that is considered more reliable by privacy advocates, then Signal is the EFF’s preferred platform, although that too is not without some caveats. "The argument from Telegram is, 'You should trust us because we tell you that we're trustworthy,'" Maréchal said. "It's really in the eye of the beholder whether that's something you want to buy into."
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